we used a 22 bp forked duplex substrate to determine whether acetylation of WRN affects its helicase activity
aks are due to free radicals in these reactions. Depending on its concentration, H2O2...
Materials and Methods Cell Culture and Transfections Human cervical carcinoma HeLa cells were cultured as described
n of the mitochondrial protein aconitase, a well-established method to monitor mitophagy, we confirmed...
The fold stimulation was calculated for each condition by dividing the C-peptide concentration released in response to stimulatory conditions by the C-peptide concentration in the basal medium
g over night. Images of crystal violet stained inserts were taken with an AxioVert...
We envisaged that the introduction of constitutively expressed Pax4 might bestow a selective advantage on the definitive endoderm cells that form spontaneously in EBs derived from cells and enhance their differentiation towards pancreatic b-cell lineage
erefore developed a cell culture model to explore the effects of type 1 IFNs...
The fold stimulation was calculated for each condition by dividing the C-peptide concentration released in response to stimulatory conditions by the C-peptide concentration in the basal medium
ers. In contrast, tumor cell surface expression of CD46, the putative ColoAd1 receptor, appears...
Lifespan is thought to be determined by the accumulation of cellular damage arising from ROS although recent evidence from C. elegans suggests that ROS might in fact be responsible for extending lifespan
ed down onto the microarray slide, which was mounted into the AgilentTM Microarray Hybridization...
the accumulation of point mutations may lead to the spontaneous occurrence of the first GALA-LRR and due to the structural complementarities
Research Center; and of a deceased autologous transplant donor through the Bone Marrow Transplant...
After stimulation, in splenocytes obtained from TIRC7 deficient mice apoptosis was decreased in comparison to WT splenocytes indicating that TIRC7 is central to the induction of apoptosis in lymphocytes
n of eIF2a in the peptide expressing cells. It is likely that another kinase...
Flow cytometry using an anti-Fc protein antibody revealed that human sHLADRa2 exclusively bound to the surface of TIRC7-expressing COS7 cells whereas no binding was observed in non-transfected control COS7 cells
se discovery rates than when using statistical t-tests. Because RPKM values are determined on...
In dynamic cycling studies, bubble size was smoothly varied over the same size range as in the quasi-static studies
GIP antagonists were made in lean animals. Recently, Gault et al. reported that prolonged...