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The final results of this experiment, summarized in Fig. six, demonstrate that the enforced expression of MLL-AF9 pushed by the UMG-LV6-MA9 vector (Fig. 6A, 6B) resulted in a proliferative benefit (Fig. 6C) and in a significantly increased frequency of immature, colony-forming cells (Fig. 6D) in transduced CD34+ cells

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UMG-LV11 encourages productive transgene- and reporter gene expression in human hematopoietic mobile lines. The...