Product Name :
Prostaglandin E2
Sequence:
Purity:
≥97% (HPLC)
Molecular Weight:
352.5
Solubility :
Soluble in 100% ethanol, DMSO or dimethylformamide (100mg/ml); soluble in acetone. Sparingly soluble in PBS, pH 7.2 (5mg/ml).
Appearance:
White to off-white crystalline powder.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Stable for at least 2 years after receipt when stored at -20°C.{{67763-87-5} medchemexpress|{67763-87-5} Purity & Documentation|{67763-87-5} References|{67763-87-5} supplier} Avoid basic solutions (pH > 7.{{2444815-84-1} web|{2444815-84-1} Biological Activity|{2444815-84-1} Data Sheet|{2444815-84-1} supplier} 4), since Prostaglandin E2 will degrade to PGA and PGB. We do not recommend storing aqueous solutions for more than one day.
Description:
Prostanoid receptor ligand Biosynthesis in numerous cell types. Potent vasodilator. Exerts both anti- and proinflammatory activities by inhibition of mediator release and enhancement of mediator action. Stimulates bone resorption. Synergizes with LTB4. Facilitates replication of AIDS virus. Regulates sleep/wake cycle. Thermoregulatory action in the CNS.PMID:30252291 Induces LHRH release from rat median eminence. Regulates renal hemodynamics and sodium excretion. One of the primary cyclooxygenase (COX) products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) of PGE2 for these receptors range from 1-10nM depending on the receptor subtype and tissue. Regulates vertebrate hematopoietic stem cell homeostasis.
CAS :
363-24-6
Solubility:
Soluble in 100% ethanol, DMSO or dimethylformamide (100mg/ml); soluble in acetone. Sparingly soluble in PBS, pH 7.2 (5mg/ml).
Formula:
C20H32O5
Additional Information :
| Alternative Name PGE2 | Appearance White to off-white crystalline powder. | CAS 363-24-6 | Couple Target Prostanoid receptor | Couple Type Ligand | Formula C20H32O5 | MI 14: 7877 | MW 352.5 | Purity ≥97% (HPLC) | Solubility Soluble in 100% ethanol, DMSO or dimethylformamide (100mg/ml); soluble in acetone. Sparingly soluble in PBS, pH 7.2 (5mg/ml). | Unit of Measure (UM) mg
