Product Name :
KS106
Description:
KS106 is a potent ALDH inhibitor with IC5os of 334, 2137, 360 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxicKS106 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS106 induces apoptosis and cell cycle arrest at the G2/M phase[1]
CAS:
2408477-50-7
Molecular Weight:
474.29
Formula:
C18H15BrF3N3O2S
Chemical Name:
Smiles :
Br.NC(=N)SCC1C=CC(CN2C3=CC=C(C=C3C(=O)C2=O)C(F)(F)F)=CC=1
InChiKey:
AHVSKNDQJSDEMD-UHFFFAOYSA-N
InChi :
InChI=1S/C18H14F3N3O2S.BrH/c19-18(20,21)12-5-6-14-13(7-12)15(25)16(26)24(14)8-10-1-3-11(4-2-10)9-27-17(22)23;/h1-7H,8-9H2,(H3,22,23);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{β-Amanitin} site|{β-Amanitin} Antibody-drug Conjugate/ADC Related|{β-Amanitin} Technical Information|{β-Amanitin} Description|{β-Amanitin} supplier|{β-Amanitin} Cancer}
Additional information:
KS106 is a potent ALDH inhibitor with IC5os of 334, 2137, 360 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.{{Fisetin} web|{Fisetin} Cell Cycle/DNA Damage|{Fisetin} Purity & Documentation|{Fisetin} In Vivo|{Fisetin} custom synthesis|{Fisetin} Epigenetic Reader Domain} KS106 shows antiproliferative and anticancer effects with low low toxicKS106 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation.PMID:23795974 KS106 induces apoptosis and cell cycle arrest at the G2/M phase[1]|Product information|CAS Number: 2408477-50-7|Molecular Weight: 474.29|Formula: C18H15BrF3N3O2S|Smiles: Br.NC(=N)SCC1C=CC(CN2C3=CC=C(C=C3C(=O)C2=O)C(F)(F)F)=CC=1|InChiKey: AHVSKNDQJSDEMD-UHFFFAOYSA-N|InChi: InChI=1S/C18H14F3N3O2S.BrH/c19-18(20,21)12-5-6-14-13(7-12)15(25)16(26)24(14)8-10-1-3-11(4-2-10)9-27-17(22)23;/h1-7H,8-9H2,(H3,22,23);1H|Technical Data|Appearance: induces apoptosis and cell cycle arrest at the G2/M phase[1]|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
