Product Name :
BIX 02565
Description:
BIX 02565 is a novel RSK2 inhibitor with IC50 value of 1 nM. BIX 02565 inhibits adrenergic ɑ1A-, ɑ1B-, ɑ1D-, ɑ2A-, β2- and imidazoline I2 receptors with IC50 values ranging from 0.052 to 1.820 μM. These receptors played important roles in the regulation of vascular tone and cardiac function
CAS:
1311367-27-7
Molecular Weight:
458.56
Formula:
C26H30N6O2
Chemical Name:
(5R)-N-{1-[3-(dimethylamino)propyl]-1H-1,3-benzodiazol-2-yl}-5-methyl-1-oxo-1H,2H,3H,4H,5H-[1,4]diazepino[1,2-a]indole-8-carboxamide
Smiles :
CN(C)CCCN1C(NC(=O)C2=CC3=C(C=C4C(=O)NCC[C@@H](C)N34)C=C2)=NC2=CC=CC=C12
InChiKey:
ZHMXXVNQAFCXKK-QGZVFWFLSA-N
InChi :
InChI=1S/C26H30N6O2/c1-17-11-12-27-25(34)23-15-18-9-10-19(16-22(18)32(17)23)24(33)29-26-28-20-7-4-5-8-21(20)31(26)14-6-13-30(2)3/h4-5,7-10,15-17H,6,11-14H2,1-3H3,(H,27,34)(H,28,29,33)/t17-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ivermectin} site|{Ivermectin} Autophagy|{Ivermectin} Protocol|{Ivermectin} References|{Ivermectin} manufacturer|{Ivermectin} Autophagy}
Shelf Life:
≥360 days if stored properly.{{Mirvetuximab} medchemexpress|{Mirvetuximab} Cell Cycle/DNA Damage|{Mirvetuximab} Biological Activity|{Mirvetuximab} References|{Mirvetuximab} custom synthesis|{Mirvetuximab} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24513027
Additional information:
BIX 02565 is a novel RSK2 inhibitor with IC50 value of 1 nM. BIX 02565 inhibits adrenergic ɑ1A-, ɑ1B-, ɑ1D-, ɑ2A-, β2- and imidazoline I2 receptors with IC50 values ranging from 0.052 to 1.820 μM. These receptors played important roles in the regulation of vascular tone and cardiac function|Product information|CAS Number: 1311367-27-7|Molecular Weight: 458.56|Formula: C26H30N6O2|Chemical Name: (5R)-N-{1-[3-(dimethylamino)propyl]-1H-1,3-benzodiazol-2-yl}-5-methyl-1-oxo-1H,2H,3H,4H,5H-[1,4]diazepino[1,2-a]indole-8-carboxamide|Smiles: CN(C)CCCN1C(NC(=O)C2=CC3=C(C=C4C(=O)NCC[C@@H](C)N34)C=C2)=NC2=CC=CC=C12|InChiKey: ZHMXXVNQAFCXKK-QGZVFWFLSA-N|InChi: InChI=1S/C26H30N6O2/c1-17-11-12-27-25(34)23-15-18-9-10-19(16-22(18)32(17)23)24(33)29-26-28-20-7-4-5-8-21(20)31(26)14-6-13-30(2)3/h4-5,7-10,15-17H,6,11-14H2,1-3H3,(H,27,34)(H,28,29,33)/t17-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
