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Rac, a compact GTPase that belongs for the Rho household, controls quite a few cellular functions, which includes actin cytoskeleton reorganization, motility, and cell cycle progression. Rac activation status is controlled mainly by guanine nucleotide exchange aspects (GEFs) that market GTP loading and thereby activate Rac, and by GTPase activating proteins (GAPs) that inactivate Rac by accelerating GTP hydrolysis. Amongst the many Rac-GAP households, chimaerins.
