Of 70 and 66 /mL, respectively) [51]. Additionally, phenolic-rich extracts from different populations
Of 70 and 66 /mL, respectively) [51]. Moreover, phenolic-rich extracts from diverse populations of Salvia fruticosa [52] and aqueous and methanolic extracts of Salvia cadmica from Turkey [53], had been demonstrated to scavenge DPPHand ABTS, and to lessen GNE-371 Epigenetic Reader Domain ferric ion too. In these studies, GYKI 52466 web rosmarinic acid was detected because the major compound, ranging from 20.six to 41.9 mg/g extract [53]. In excellent agreement with these outcomes, other Salvia polar extracts, for instance S. amplexicaulis [49], Salvia halophila [54], Salvia virgata, Salvia persica, Salvia cereal and Salvia reuterana [40], had been shown to inhibit -carotene bleaching, in some circumstances with equal capacity to those of your normal compounds. Similarly, the potential of Salvia species to inhibit lipid peroxidation, as estimated by TBARS assay, was reported for an ethyl acetate extract of S. halophila, which exerted an inhibitory ability equivalent towards the industrial antioxidant BHT [54]. In addition, amongst 5 solvent extracts in the aerial components of Salvia pachyphylla, the ethyl acetate extract was one of the most active according to DPPHscavenging assay (EC50 = 0.28 mg/ml) [55]. Furthermore, Asadi et al [56] reported the scavenging potential of six Salvia species methanolic extracts as varying between 1 to 487.1 mg ascorbic acid equivalent /g dried extract, within the order: Salvia hydrangea, Salvia macilenta Salvia multicalis, Salvia sclarea Salvia xanthocheila and Salvia lachnocalyx [56]. Additionally, Kostic et al. [57] reported great antioxidant potential of ethanolic extracts of S. sclarea, as estimated via DPPH(EC50 = 27.eight /mL) and inhibition of carotene (EC50 = 19.1 /mL) solutions. Likewise, methanolic extracts of S. syriaca and Salvia nemorosa collected in Iran have been shown to possess a scavenging capacity towards DPPHsimilar to that of BHT [51,58]. The authors discovered a very good correlation amongst total phenolic compounds (TPC) and flavonoids (TFC), and their antioxidant activities, highlighting their richness in rosmarinic acid as well as quercetin and its glycosides. Other methanolic extracts of a collection of Salvia species, like Salvia eremophila, Salvia santolinifolia, S. nemorosa and Salvia atropatana, were demonstrated to be good DPPHscavengers also [16], and these of S. sclarea and S. nemorosa have been even claimed to be 1.4.2 instances reduce than those of BHT [40]. The high antioxidant prospective of the two latter extracts was also attested to by other chemical in vitro tests, namely ORAC and ABTS [59]. Though much less studied, aqueous extracts obtained from Salvia plants have also been reported to be promising antioxidant agents. Within this regard, an S. officinalis decoction extract, wealthy in quinic acid, protocatechuic acid, gallic acid and salvianolic acid, was shown to inhibit -carotene bleaching with IC50 values two.7-fold larger than BHT [60]. In a further study, our group demonstrated that the decoctions of Salvia africana, Salvia officinalis `Icterina’, Salvia mexicana [26] and Salvia elegans [27], had DPPHEC50 values inside the selection of six.6 0.7 and ten.7 two.1 /mL, using a potency of about half or the exact same order of ascorbic acid. Likewise, decoctions of S. africana, S. officinalis `Icterina’ and S. mexicana have been shown to hamper lipidAppl. Sci. 2021, 11,four ofperoxidation, as measured by TBARS assay, in the similar magnitude of trolox [26]. Furthermore, a decoction of Salvia apiana was also emphasized for its capacity to prevent lipid peroxidation events [25]. Moreover, decoctions of S. elegans, S. officinalis an.