Product Name :
Phleomycin
Description:
Phleomycin is an anticancer glycopeptide antibiotic found in Streptomyces verticillus, which cause DNA cleavage. Phleomycin binds and intercalates DNA to damage the integrity of the double helix, which is similar to Bleomycin (HY-17565A).
CAS:
11006-33-0
Molecular Weight:
1527.53
Formula:
C55H87ClCuN20O21S2
Chemical Name:
copper(2+) (2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-2-[(6-amino-2-1-[(2-amino-2-carbamoylethyl)amino]-2-carbamoylethyl-5-methylpyrimidin-4-yl)formamido]-2-(4-[(1-[2-(4-4-[(4-carbamimidamidobutyl)carbamoyl]-1,3-thiazol-2-yl-4,5-dihydro-1,3-thiazol-2-yl)ethyl]carbamoyl-2-hydroxypropyl)carbamoyl]-3-hydroxy-4-methylbutan-2-ylcarbamoyl)-1-(1H-imidazol-4-yl)ethoxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl carbamate hydrochloride
Smiles :
Cl.[Cu+2].CC1C(=NC(=NC=1N)C(CC(N)=O)NCC(N)C(N)=O)C(=O)NC(C(O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)C1=CNC=N1)C(=O)NC(C)C(O)C(C)C(=O)NC(C(C)O)C(=O)NCCC1=NC(CS1)C1=NC(=CS1)C(=O)NCCCCNC(N)=N
InChiKey:
FYFZNIOBQUWNRM-GEYAUAICSA-N
InChi :
InChI=1S/C55H86N20O21S2.ClH.Cu/c1-19-32(72-45(75-43(19)58)24(11-30(57)79)67-12-23(56)44(59)85)49(89)74-34(40(25-13-63-18-68-25)94-53-42(38(83)36(81)28(14-76)93-53)95-52-39(84)41(96-55(62)91)37(82)29(15-77)92-52)50(90)69-21(3)35(80)20(2)46(86)73-33(22(4)78)48(88)65-10-7-31-70-27(17-97-31)51-71-26(16-98-51)47(87)64-8-5-6-9-66-54(60)61;;/h13,16,18,20-24,27-29,33-42,52-53,67,76-78,80-84H,5-12,14-15,17,56H2,1-4H3,(H2,57,79)(H2,59,85)(H2,62,91)(H,63,68)(H,64,87)(H,65,88)(H,69,90)(H,73,86)(H,74,89)(H2,58,72,75)(H4,60,61,66);1H;/q;;+2/t20?,21?,22?,23?,24?,27?,28-,29+,33?,34?,35?,36+,37+,38-,39-,40?,41-,42-,52+,53-;;/m0.P7C3 Technical Information ./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Phleomycin is an anticancer glycopeptide antibiotic found in Streptomyces verticillus, which cause DNA cleavage. Phleomycin binds and intercalates DNA to damage the integrity of the double helix, which is similar to Bleomycin (HY-17565A).|Product information|CAS Number: 11006-33-0|Molecular Weight: 1527.53|Formula: C55H87ClCuN20O21S2|Chemical Name: copper(2+) (2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-2-[(6-amino-2-1-[(2-amino-2-carbamoylethyl)amino]-2-carbamoylethyl-5-methylpyrimidin-4-yl)formamido]-2-(4-[(1-[2-(4-4-[(4-carbamimidamidobutyl)carbamoyl]-1,3-thiazol-2-yl-4,5-dihydro-1,3-thiazol-2-yl)ethyl]carbamoyl-2-hydroxypropyl)carbamoyl]-3-hydroxy-4-methylbutan-2-ylcarbamoyl)-1-(1H-imidazol-4-yl)ethoxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl carbamate hydrochloride|Smiles: Cl.Fluticasone propionate Technical Information [Cu+2].PMID:33252507 CC1C(=NC(=NC=1N)C(CC(N)=O)NCC(N)C(N)=O)C(=O)NC(C(O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)C1=CNC=N1)C(=O)NC(C)C(O)C(C)C(=O)NC(C(C)O)C(=O)NCCC1=NC(CS1)C1=NC(=CS1)C(=O)NCCCCNC(N)=N|InChiKey: FYFZNIOBQUWNRM-GEYAUAICSA-N|InChi: InChI=1S/C55H86N20O21S2.ClH.Cu/c1-19-32(72-45(75-43(19)58)24(11-30(57)79)67-12-23(56)44(59)85)49(89)74-34(40(25-13-63-18-68-25)94-53-42(38(83)36(81)28(14-76)93-53)95-52-39(84)41(96-55(62)91)37(82)29(15-77)92-52)50(90)69-21(3)35(80)20(2)46(86)73-33(22(4)78)48(88)65-10-7-31-70-27(17-97-31)51-71-26(16-98-51)47(87)64-8-5-6-9-66-54(60)61;;/h13,16,18,20-24,27-29,33-42,52-53,67,76-78,80-84H,5-12,14-15,17,56H2,1-4H3,(H2,57,79)(H2,59,85)(H2,62,91)(H,63,68)(H,64,87)(H,65,88)(H,69,90)(H,73,86)(H,74,89)(H2,58,72,75)(H4,60,61,66);1H;/q;;+2/t20?,21?,22?,23?,24?,27?,28-,29+,33?,34?,35?,36+,37+,38-,39-,40?,41-,42-,52+,53-;;/m0../s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 100 mg/mL (Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
