Product Name :
N-Boc-PEG2-bromide
Description:
N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
164332-88-1
Molecular Weight:
268.15
Formula:
C9H18BrNO3
Chemical Name:
tert-butyl N-[2-(2-bromoethoxy)ethyl]carbamate
Smiles :
CC(C)(C)OC(=O)NCCOCCBr
InChiKey:
DMOPZPBTLCZSGL-UHFFFAOYSA-N
InChi :
InChI=1S/C9H18BrNO3/c1-9(2,3)14-8(12)11-5-7-13-6-4-10/h4-7H2,1-3H3,(H,11,12)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Irbesartan Cancer
Shelf Life:
≥12 months if stored properly.Imipramine In Vivo
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
N-Boc-PEG2-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.PMID:33358311 N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).|Product information|CAS Number: 164332-88-1|Molecular Weight: 268.15|Formula: C9H18BrNO3|Chemical Name: tert-butyl N-[2-(2-bromoethoxy)ethyl]carbamate|Smiles: CC(C)(C)OC(=O)NCCOCCBr|InChiKey: DMOPZPBTLCZSGL-UHFFFAOYSA-N|InChi: InChI=1S/C9H18BrNO3/c1-9(2,3)14-8(12)11-5-7-13-6-4-10/h4-7H2,1-3H3,(H,11,12)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|
