Phosphoserine polyclonal antibody

Description:
Protein phosphorylation is a complex biochemical process that is regulated by protein kinases that catalyze the transfer of the gamma-P of ATP to a recipient protein that acts as a substrate. This post-translational modification is primarily directed onto serine, threonine, and tyrosine amino acid residues within a protein. Changes in the phosphorylation status of phosphoproteins can alter their biological function, and aberrations in signal transduction cascades have been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders. Western blot analysis of human MMRU melanoma cells probed with Phosphoserine, pAb. Top (from the left): MMRU cells treated with 0 (A), 50 (B), 200 (C), 400 (D) l long wavelength UV, or 0.1µM of okadaic acid (E). Bottom: Same samples probed with β-actin antibody (control). Western blot analysis of human MMRU melanoma cells probed with Phosphoserine, pAb. Top (from the left): MMRU cells treated with 0 (A), 50 (B), 200 (C), 400 (D) l long wavelength UV, or 0.1µM of okadaic acid (E). Bottom: Same samples probed with β-actin antibody (control).