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PC-12 (heat shocked) , (cell lysate)
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The PC-12 cell line was derived from a transplantable rat adrenal pheochromocytoma.{{38966-21-1} MedChemExpress|{38966-21-1} Purity & Documentation|{38966-21-1} In stock|{38966-21-1} custom synthesis} Cellular stressors such as heat shock and oxidative stress result in the activation of heat shock protein gene expression by transcriptional regulators such as HSF1.{{4474-91-3} MedChemExpress|{4474-91-3} Purity & Documentation|{4474-91-3} Purity|{4474-91-3} manufacturer} Heat shock proteins play an important role in both normal cellular homeostasis as well as cell survival during and after cellular stress.PMID:31194447
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| Application Notes Western blot control. | Concentration 2mg/ml | Formulation Liquid. In SDS-PAGE sample buffer, pH 6.8, heated for 10 min. at 70°C and containing 40mM TRIS-HCl, 1% SDS, 50mM DTT, 7.5% glycerol, and 0.003% bromophenol blue. | Source Rat