Product Name :
FM-381
CAS No.:
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CN(C)C(=O)/C(=C/C1=CC=C(O1)C2=NC3=CN=C4[NH]C=CC4=C3[N]2C5CCCCC5)C#N
Product Description :
FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.{{208538-73-2} medchemexpress|{208538-73-2} Purity & Documentation|{208538-73-2} In stock|{208538-73-2} supplier}
Formula:
C24H24N6O2
Molecular Weight :
428.49
Synonyms:
Additional Information:
|Formula C24H24N6O2 ; |Molecular Weight 428.{{113507-06-5} site|{113507-06-5} Biological Activity|{113507-06-5} Data Sheet|{113507-06-5} manufacturer} 49 ; |SMILES CN(C)C(=O)/C(=C/C1=CC=C(O1)C2=NC3=CN=C4[NH]C=CC4=C3[N]2C5CCCCC5)C#N ; |Product Description FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.PMID:30725946 ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO