Product Name :
C188-9
CAS No.:
432001-19-9
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=CC=C(C=C1)[S](=O)(=O)NC2=CC(=C(O)C3=CC=CC=C23)C4=C(O)C=CC5=C4C=CC=C5
Product Description :
C188-9 is a potent inhibitor of STAT3 that binds to STAT3 with high affinity (KD=4.{{1523406-39-4} site|{1523406-39-4} Protocol|{1523406-39-4} Description|{1523406-39-4} custom synthesis} 7±0.4 nM). C188-9 is well tolerated in mice, shows good oral bioavailability, and is concentrated in tumors.
Formula:
C27H21NO5S
Molecular Weight :
471.{{110078-46-1} site|{110078-46-1} Technical Information|{110078-46-1} Description|{110078-46-1} custom synthesis} 52
Synonyms:
Additional Information:
|CAS No. 432001-19-9 ; |Formula C27H21NO5S ; |Molecular Weight 471.52 ; |SMILES COC1=CC=C(C=C1)[S](=O)(=O)NC2=CC(=C(O)C3=CC=CC=C23)C4=C(O)C=CC5=C4C=CC=C5 ; |Target STAT3 ; |Product Description C188-9 is a potent inhibitor of STAT3 that binds to STAT3 with high affinity (KD=4.PMID:28613708 7±0.4 nM). C188-9 is well tolerated in mice, shows good oral bioavailability, and is concentrated in tumors. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO
