Product Name :
BMS-962212
Description:
BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity.
CAS:
1430114-34-3
Molecular Weight:
659.07
Formula:
C32H28ClFN8O5
Chemical Name:
4-[(1S)-2-[(2E)-3-[3-chloro-2-fluoro-6-(1H-1,2,3,4-tetrazol-1-yl)phenyl]prop-2-enoyl]-5-(4-methyl-2-oxopiperazin-1-yl)-1,2,3,4-tetrahydroisoquinoline-1-amido]benzoic acid
Smiles :
CN1CC(=O)N(CC1)C1=CC=CC2[C@@H](C(=O)NC3C=CC(=CC=3)C(O)=O)N(CCC=21)C(=O)/C=C/C1=C(F)C(Cl)=CC=C1N1C=NN=N1
InChiKey:
WYFCZWSWFGJODV-MIANJLSGSA-N
InChi :
InChI=1S/C32H28ClFN8O5/c1-39-15-16-40(28(44)17-39)25-4-2-3-22-21(25)13-14-41(30(22)31(45)36-20-7-5-19(6-8-20)32(46)47)27(43)12-9-23-26(42-18-35-37-38-42)11-10-24(33)29(23)34/h2-12,18,30H,13-17H2,1H3,(H,36,45)(H,46,47)/b12-9+/t30-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Abraxane} MedChemExpress|{Abraxane} Cell Cycle/DNA Damage|{Abraxane} Protocol|{Abraxane} Data Sheet|{Abraxane} manufacturer|{Abraxane} Epigenetic Reader Domain}
Additional information:
BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor .{{Voriconazole} site|{Voriconazole} Fungal|{Voriconazole} Protocol|{Voriconazole} Data Sheet|{Voriconazole} supplier|{Voriconazole} Cancer} BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination.PMID:33092667 BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity.|Product information|CAS Number: 1430114-34-3|Molecular Weight: 659.07|Formula: C32H28ClFN8O5|Chemical Name: 4-[(1S)-2-[(2E)-3-[3-chloro-2-fluoro-6-(1H-1,2,3,4-tetrazol-1-yl)phenyl]prop-2-enoyl]-5-(4-methyl-2-oxopiperazin-1-yl)-1,2,3,4-tetrahydroisoquinoline-1-amido]benzoic acid|Smiles: CN1CC(=O)N(CC1)C1=CC=CC2[C@@H](C(=O)NC3C=CC(=CC=3)C(O)=O)N(CCC=21)C(=O)/C=C/C1=C(F)C(Cl)=CC=C1N1C=NN=N1|InChiKey: WYFCZWSWFGJODV-MIANJLSGSA-N|InChi: InChI=1S/C32H28ClFN8O5/c1-39-15-16-40(28(44)17-39)25-4-2-3-22-21(25)13-14-41(30(22)31(45)36-20-7-5-19(6-8-20)32(46)47)27(43)12-9-23-26(42-18-35-37-38-42)11-10-24(33)29(23)34/h2-12,18,30H,13-17H2,1H3,(H,36,45)(H,46,47)/b12-9+/t30-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
