Product Name :
Zotarolimus(ABT-578)
CAS No.:
221877-54-9
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1CC(CCC1[N]2C=NN=N2)CC(C)C3CC(=O)C(C)/C=C(C)/C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC4CCC(C)C(O)(O4)C(=O)C(=O)N5CCCCC5C(=O)O3)OC
Product Description :
Zotarolimus (ABT-578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.
Formula:
C52H79N5O12
Molecular Weight :
966.21
Synonyms:
Additional Information:
|CAS No.{{54-36-4} MedChemExpress|{54-36-4} Technical Information|{54-36-4} Formula|{54-36-4} supplier} 221877-54-9 ; |Formula C52H79N5O12 ; |Molecular Weight 966.21 ; |SMILES COC1CC(CCC1[N]2C=NN=N2)CC(C)C3CC(=O)C(C)/C=C(C)/C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(C)/C(CC4CCC(C)C(O)(O4)C(=O)C(=O)N5CCCCC5C(=O)O3)OC ; |Target FKBP-12 ; |Product Description Zotarolimus (ABT-578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.{{130308-48-4} site|{130308-48-4} Biological Activity|{130308-48-4} Data Sheet|{130308-48-4} supplier} 8 nM.PMID:25905190 ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO
