Product Name :
VER 155008
CAS No.:
1134156-31-2
Purity :
> 98%
Shipping:
Shipped at room temperature.
Storage :
Store at or below –20 °C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
SMILES:
Product Description :
VER-155002 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM). The compound inhibits proliferation of several colon and breast cancer cell lines, induces caspase dependent apoptosis in BT474 cells and down regulates expression of Her2 and Raf-1 in HCT116 cells.
Formula:
C25H23Cl2N7O4
Molecular Weight :
556.{{931402-35-6} site|{931402-35-6} Technical Information|{931402-35-6} In Vitro|{931402-35-6} manufacturer} 4
Synonyms:
adenosine-derived inhibitor, VER155008, VER-155008, me 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile
Additional Information:
|CAS No.{{374101-64-1} MedChemExpress|{374101-64-1} Biological Activity|{374101-64-1} References|{374101-64-1} manufacturer} 1134156-31-2 ; |Synonyms adenosine-derived inhibitor, VER155008, VER-155008, me 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile ; |Formula C25H23Cl2N7O4 ; |Molecular Weight 556.PMID:20301472 4 ; |Product Description VER-155002 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM). The compound inhibits proliferation of several colon and breast cancer cell lines, induces caspase dependent apoptosis in BT474 cells and down regulates expression of Her2 and Raf-1 in HCT116 cells. ; |Format Solid ; |Purity > 98% ; |Shipping Shipped at room temperature. ; |Storage Store at or below –20 °C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. ; |Solubility Overview Soluble in DMSO