Product Name :
Spaglumic Acid
Description:
Spaglumic Acid (N-Acetylaspartylglutamic acid) is a neuropeptide found in millimolar concentrations in brain.
CAS:
3106-85-2
Molecular Weight:
304.25
Formula:
C11H16N2O8
Chemical Name:
(2S)-2-[(2R)-3-carboxy-2-acetamidopropanamido]pentanedioic acid
Smiles :
CC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O
InChiKey:
OPVPGKGADVGKTG-NKWVEPMBSA-N
InChi :
InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{GW 501516} medchemexpress|{GW 501516} Agonist|{GW 501516} NF-κB|{GW 501516} Biological Activity|{GW 501516} Description|{GW 501516} supplier}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Spaglumic Acid (N-Acetylaspartylglutamic acid) is a neuropeptide found in millimolar concentrations in brain.|Product information|CAS Number: 3106-85-2|Molecular Weight: 304.25|Formula: C11H16N2O8|Chemical Name: (2S)-2-[(2R)-3-carboxy-2-acetamidopropanamido]pentanedioic acid|Smiles: CC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O|InChiKey: OPVPGKGADVGKTG-NKWVEPMBSA-N|InChi: InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 250 mg/mL (821.{{Pozelimab} medchemexpress|{Pozelimab} Complement System|{Pozelimab} Technical Information|{Pozelimab} References|{Pozelimab} manufacturer|{Pozelimab} Cancer} 69 mM; Need ultrasonic).PMID:24220671 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Spaglumic Acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of Spaglumic Acid and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders.|Products are for research use only. Not for human use.|
