Product Name :
Psicofuranine
Description:
Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5′-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth.
CAS:
1874-54-0
Molecular Weight:
297.27
Formula:
C11H15N5O5
Chemical Name:
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-2,5-bis(hydroxymethyl)oxolane-3,4-diol
Smiles :
NC1=NC=NC2=C1N=CN2[C@]1(CO)O[C@H](CO)[C@@H](O)[C@H]1O
InChiKey:
BNZYRKVSCLSXSJ-IOSLPCCCSA-N
InChi :
InChI=1S/C11H15N5O5/c12-9-6-10(14-3-13-9)16(4-15-6)11(2-18)8(20)7(19)5(1-17)21-11/h3-5,7-8,17-20H,1-2H2,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ociperlimab} medchemexpress|{Ociperlimab} Biological Activity|{Ociperlimab} In Vivo|{Ociperlimab} custom synthesis|{Ociperlimab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5′-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth.|Product information|CAS Number: 1874-54-0|Molecular Weight: 297.27|Formula: C11H15N5O5|Chemical Name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-2,5-bis(hydroxymethyl)oxolane-3,4-diol|Smiles: NC1=NC=NC2=C1N=CN2[C@]1(CO)O[C@H](CO)[C@@H](O)[C@H]1O|InChiKey: BNZYRKVSCLSXSJ-IOSLPCCCSA-N|InChi: InChI=1S/C11H15N5O5/c12-9-6-10(14-3-13-9)16(4-15-6)11(2-18)8(20)7(19)5(1-17)21-11/h3-5,7-8,17-20H,1-2H2,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (168.{{HBC} web|{HBC} Cell Cycle/DNA Damage|{HBC} Technical Information|{HBC} Purity|{HBC} supplier|{HBC} Autophagy} 20 mM; Need ultrasonic).PMID:23399686 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Psicofuranine specifically inhibits bacterial GMP synthase as demonstrated by isolation of Psicofuranine-resistant Escherichia coli mutants with mutations in the gene encoding GMP synthase and inhibition of bacterial growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth with an IC50 of 0.3 mM. The Psicofuranine inhibitory concentration is similar to that of E. coli.|Products are for research use only. Not for human use.|
