Product Name :
(±)-Huperzine A
Description:
(±)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer’s disease (AD). IC50 value:Target: AChE(±)-Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The (±)-Huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation. (±)-Huperzine A is a potential therapeutic agent for Alzheimer’s disease.
CAS:
120786-18-7
Molecular Weight:
242.32
Formula:
C15H18N2O
Chemical Name:
1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.0²,⁷]trideca-2(7),3,10-trien-5-one
Smiles :
CC1CC2(N)C(=CC)C(CC3NC(=O)C=CC2=3)C=1
InChiKey:
ZRJBHWIHUMBLCN-QDEBKDIKSA-N
InChi :
InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bisphenol A} site|{Bisphenol A} Metabolic Enzyme/Protease|{Bisphenol A} Biological Activity|{Bisphenol A} In Vivo|{Bisphenol A} manufacturer|{Bisphenol A} Epigenetic Reader Domain}
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(±)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer’s disease (AD). IC50 value:Target: AChE(±)-Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The (±)-Huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation. (±)-Huperzine A is a potential therapeutic agent for Alzheimer’s disease.|Product information|CAS Number: 120786-18-7|Molecular Weight: 242.32|Formula: C15H18N2O|Chemical Name: 1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.{{Calcifediol} site|{Calcifediol} Vitamin D Related/Nuclear Receptor|{Calcifediol} Biological Activity|{Calcifediol} In Vitro|{Calcifediol} manufacturer|{Calcifediol} Cancer} 3.PMID:24025603 1.0²,⁷]trideca-2(7),3,10-trien-5-one|Smiles: CC1CC2(N)C(=CC)C(CC3NC(=O)C=CC2=3)C=1|InChiKey: ZRJBHWIHUMBLCN-QDEBKDIKSA-N|InChi: InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
