Product Name :
(R)-(4′-Hydroxy)-5, 7-dihydroxy-4-chromanone
Description:
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells.
CAS:
849727-88-4
Molecular Weight:
286.28
Formula:
C16H14O5
Chemical Name:
(3R)-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-3,4-dihydro-2H-1-benzopyran-4-one
Smiles :
OC1C=C(O)C2C(=O)[C@H](CC3C=CC(O)=CC=3)COC=2C=1
InChiKey:
FIASLUPJXGTCKM-SNVBAGLBSA-N
InChi :
InChI=1S/C16H14O5/c17-11-3-1-9(2-4-11)5-10-8-21-14-7-12(18)6-13(19)15(14)16(10)20/h1-4,6-7,10,17-19H,5,8H2/t10-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells.|Product information|CAS Number: 849727-88-4|Molecular Weight: 286.28|Formula: C16H14O5|Chemical Name: (3R)-5,7-dihydroxy-3-[(4-hydroxyphenyl)methyl]-3,4-dihydro-2H-1-benzopyran-4-one|Smiles: OC1C=C(O)C2C(=O)[C@H](CC3C=CC(O)=CC=3)COC=2C=1|InChiKey: FIASLUPJXGTCKM-SNVBAGLBSA-N|InChi: InChI=1S/C16H14O5/c17-11-3-1-9(2-4-11)5-10-8-21-14-7-12(18)6-13(19)15(14)16(10)20/h1-4,6-7,10,17-19H,5,8H2/t10-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Clemizole} web|{Clemizole} Histamine Receptor|{Clemizole} TGF-beta/Smad|{Clemizole} Purity & Documentation|{Clemizole} In Vivo|{Clemizole} manufacturer} |Shelf Life: ≥12 months if stored properly.{{Asundexian} MedChemExpress|{Asundexian} Metabolic Enzyme/Protease|{Asundexian} Technical Information|{Asundexian} References|{Asundexian} custom synthesis|{Asundexian} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:25027343 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone has an GI50 value of 35.8 µM on proliferation of human retinal microvascular endothelial cells (HRECs). (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone (10 µM, 30 µM, and 100 µM; 8 hours) significantly decreases HRECs overall tubule formation and in a dose-dependent manner.|Products are for research use only. Not for human use.|
