Product Name :
β-Secretase Inhibitor II
Description:
β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer’s disease.
CAS:
263563-09-3
Molecular Weight:
461.59
Formula:
C25H39N3O5
Chemical Name:
benzyl N-[(1S)-2-methyl-1-{[(1S)-3-methyl-1-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}butyl]carbamoyl}propyl]carbamate
Smiles :
CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC1C=CC=CC=1)C(C)C
InChiKey:
YHUAFMGVVANYBT-FKBYEOEOSA-N
InChi :
InChI=1S/C25H39N3O5/c1-16(2)12-20(14-29)26-23(30)21(13-17(3)4)27-24(31)22(18(5)6)28-25(32)33-15-19-10-8-7-9-11-19/h7-11,14,16-18,20-22H,12-13,15H2,1-6H3,(H,26,30)(H,27,31)(H,28,32)/t20-,21-,22-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Trypsin-EDTA} site|{Trypsin-EDTA} TGF-beta/Smad|{Trypsin-EDTA} Protocol|{Trypsin-EDTA} Purity|{Trypsin-EDTA} custom synthesis}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.{{Sibeprenlimab} MedChemExpress|{Sibeprenlimab} Anti-infection|{Sibeprenlimab} Purity & Documentation|{Sibeprenlimab} In stock|{Sibeprenlimab} supplier|{Sibeprenlimab} Autophagy} 5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer’s disease.|Product information|CAS Number: 263563-09-3|Molecular Weight: 461.59|Formula: C25H39N3O5|Chemical Name: benzyl N-[(1S)-2-methyl-1-{[(1S)-3-methyl-1-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}butyl]carbamoyl}propyl]carbamate|Smiles: CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC1C=CC=CC=1)C(C)C|InChiKey: YHUAFMGVVANYBT-FKBYEOEOSA-N|InChi: InChI=1S/C25H39N3O5/c1-16(2)12-20(14-29)26-23(30)21(13-17(3)4)27-24(31)22(18(5)6)28-25(32)33-15-19-10-8-7-9-11-19/h7-11,14,16-18,20-22H,12-13,15H2,1-6H3,(H,26,30)(H,27,31)(H,28,32)/t20-,21-,22-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23672196 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II inhibits the formation of both total Aβ and Aβ1–42 in a dose-dependent manner.|Products are for research use only. Not for human use.|
