Product Name :
Tegatrabetan (BC-2059)
Description:
Tegatrabetan (BC2059) is an antagonist of β-Catenin. Tegatrabetan (BC2059) treatment disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1) and proteasomal degradation and declines in the nuclear levels of β-catenin.
CAS:
1227637-23-1
Molecular Weight:
588.74
Formula:
C28H36N4O6S2
Chemical Name:
(9E,10E)-2,7-bis(((3R,5S)-3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime
Smiles :
C[C@@H]1CN(C[C@H](C)C1)S(=O)(=O)C1C=C2/C(=N\O)/C3C=C(C=CC=3/C(=N\O)/C2=CC=1)S(=O)(=O)N1C[C@H](C)C[C@H](C)C1
InChiKey:
GAPRVZKWPDRAJA-TVRZPQSBSA-N
InChi :
InChI=1S/C28H36N4O6S2/c1-17-9-18(2)14-31(13-17)39(35,36)21-5-7-23-25(11-21)28(30-34)26-12-22(6-8-24(26)27(23)29-33)40(37,38)32-15-19(3)10-20(4)16-32/h5-8,11-12,17-20,33-34H,9-10,13-16H2,1-4H3/b29-27-,30-28+/t17-,18+,19-,20+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Mogamulizumab} medchemexpress|{Mogamulizumab} Immunology/Inflammation|{Mogamulizumab} Biological Activity|{Mogamulizumab} In Vitro|{Mogamulizumab} manufacturer|{Mogamulizumab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{SARS-CoV-2 S1 Protein (HEK293)} site|{SARS-CoV-2 S1 Protein (HEK293)} Biological Activity|{SARS-CoV-2 S1 Protein (HEK293)} In stock|{SARS-CoV-2 S1 Protein (HEK293)} custom synthesis|{SARS-CoV-2 S1 Protein (HEK293)} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24324376
Additional information:
Tegatrabetan (BC2059) is an antagonist of β-Catenin. Tegatrabetan (BC2059) treatment disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1) and proteasomal degradation and declines in the nuclear levels of β-catenin.|Product information|CAS Number: 1227637-23-1|Molecular Weight: 588.74|Formula: C28H36N4O6S2|Chemical Name: (9E,10E)-2,7-bis(((3R,5S)-3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime|Smiles: C[C@@H]1CN(C[C@H](C)C1)S(=O)(=O)C1C=C2/C(=N\O)/C3C=C(C=CC=3/C(=N\O)/C2=CC=1)S(=O)(=O)N1C[C@H](C)C[C@H](C)C1|InChiKey: GAPRVZKWPDRAJA-TVRZPQSBSA-N|InChi: InChI=1S/C28H36N4O6S2/c1-17-9-18(2)14-31(13-17)39(35,36)21-5-7-23-25(11-21)28(30-34)26-12-22(6-8-24(26)27(23)29-33)40(37,38)32-15-19(3)10-20(4)16-32/h5-8,11-12,17-20,33-34H,9-10,13-16H2,1-4H3/b29-27-,30-28+/t17-,18+,19-,20+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO 100 mg/mL (169.85 mM) Water 100 mg/mL (169.85 mM)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|W Fiskus, et al. Leukemia. 2015 Jun;29(6):1267-78.Products are for research use only. Not for human use.|
