Product Name :
Peramivir (trihydrate)
Description:
Peramivir, also known as BCX1812 and RWJ 270201, is an antiviral drug for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. Peramivir was approved to treat influenza infection in adults. (http://en.wikipedia.org/wiki/Peramivir).
CAS:
1041434-82-5
Molecular Weight:
382.45
Formula:
C15H34N4O7
Chemical Name:
(1S,2S,3S,4R)-4-[(diaminomethylidene)amino]-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid trihydrate
Smiles :
O.O.O.CC(=O)N[C@H]([C@H]1[C@@H](C[C@@H]([C@H]1O)C(O)=O)N=C(N)N)C(CC)CC
InChiKey:
RFUCJKFZFXNIGB-ZBBHRWOZSA-N
InChi :
InChI=1S/C15H28N4O4.{{Artesunate} medchemexpress|{Artesunate} Anti-infection|{Artesunate} Protocol|{Artesunate} In stock|{Artesunate} supplier|{Artesunate} Epigenetics} 3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0…/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Peramivir, also known as BCX1812 and RWJ 270201, is an antiviral drug for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. Peramivir was approved to treat influenza infection in adults. (http://en.wikipedia.org/wiki/Peramivir).|Product information|CAS Number: 1041434-82-5|Molecular Weight: 382.45|Formula: C15H34N4O7|Synonym:|RWJ 270201 trihydrate|Rapiacta trihydrate|BCX 1812 trihydrate|Chemical Name: (1S,2S,3S,4R)-4-[(diaminomethylidene)amino]-3-[(1S)-1-acetamido-2-ethylbutyl]-2-hydroxycyclopentane-1-carboxylic acid trihydrate|Smiles: O.O.O.CC(=O)N[C@H]([C@H]1[C@@H](C[C@@H]([C@H]1O)C(O)=O)N=C(N)N)C(CC)CC|InChiKey: RFUCJKFZFXNIGB-ZBBHRWOZSA-N|InChi: InChI=1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.{{SC66} MedChemExpress|{SC66} Apoptosis|{SC66} Technical Information|{SC66} Description|{SC66} custom synthesis|{SC66} Autophagy} .PMID:23554582 ./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 5 mg/mL (13.07 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Babu YS, et al. BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design. J Med Chem. 2000 Sep 21;43(19):3482-6.Young D, et al. RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza. Philos Trans R Soc Lond B Biol Sci. 2001 Dec 29;356(1416):1905-13.Products are for research use only. Not for human use.|
