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Product Name :
AS 602801

Description:
Bentamapimod, also known as AS602801 and PGL5001, is a JNK Inhibitor. AS602801 induces regression of endometriotic lesions in animal models. AS602801 interrupts immune pathways. Bentamapimod induced regression of endometriotic lesions in endometriosis rodent animal models without suppressing ER action. Endometriosis is an estrogen (ER)-dependent gynecological disease caused by the growth of endometrial tissue at extrauterine sites.

CAS:
848344-36-5

Molecular Weight:
457.55

Formula:
C25H23N5O2S

Chemical Name:
2-(1,3-benzothiazol-2-yl)-2-[2-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)pyrimidin-4-yl]acetonitrile

Smiles :
N#CC(C1=NC2=CC=CC=C2S1)C1=CC=NC(=N1)OCC1C=CC(CN2CCOCC2)=CC=1

InChiKey:
XCPPIJCBCWUBNT-UHFFFAOYSA-N

InChi :
InChI=1S/C25H23N5O2S/c26-15-20(24-28-22-3-1-2-4-23(22)33-24)21-9-10-27-25(29-21)32-17-19-7-5-18(6-8-19)16-30-11-13-31-14-12-30/h1-10,20H,11-14,16-17H2

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Poziotinib} web|{Poziotinib} Apoptosis|{Poziotinib} Biological Activity|{Poziotinib} Formula|{Poziotinib} supplier|{Poziotinib} Epigenetics}

Shelf Life:
≥360 days if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Bentamapimod, also known as AS602801 and PGL5001, is a JNK Inhibitor. AS602801 induces regression of endometriotic lesions in animal models. AS602801 interrupts immune pathways. Bentamapimod induced regression of endometriotic lesions in endometriosis rodent animal models without suppressing ER action.{{Adenosylhomocysteinase} MedChemExpress|{Adenosylhomocysteinase} Vitamin D Related/Nuclear Receptor|{Adenosylhomocysteinase} Purity & Documentation|{Adenosylhomocysteinase} Description|{Adenosylhomocysteinase} manufacturer|{Adenosylhomocysteinase} Autophagy} Endometriosis is an estrogen (ER)-dependent gynecological disease caused by the growth of endometrial tissue at extrauterine sites.PMID:29844565 |Product information|CAS Number: 848344-36-5|Molecular Weight: 457.55|Formula: C25H23N5O2S|Chemical Name: 2-(1,3-benzothiazol-2-yl)-2-[2-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)pyrimidin-4-yl]acetonitrile|Smiles: N#CC(C1=NC2=CC=CC=C2S1)C1=CC=NC(=N1)OCC1C=CC(CN2CCOCC2)=CC=1|InChiKey: XCPPIJCBCWUBNT-UHFFFAOYSA-N|InChi: InChI=1S/C25H23N5O2S/c26-15-20(24-28-22-3-1-2-4-23(22)33-24)21-9-10-27-25(29-21)32-17-19-7-5-18(6-8-19)16-30-11-13-31-14-12-30/h1-10,20H,11-14,16-17H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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