Product Name :
TRPC6-PAM-C20
Description:
TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 selectively activates TRPC6 over other TRP channels and also activates TRPA1. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50=2.37 μM).
CAS:
667427-75-0
Molecular Weight:
363.41
Formula:
C22H21NO4
Chemical Name:
3-(6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-2H-chromen-2-one
Smiles :
CC1(C)CC2C=C(OC)C(=CC=2C(=N1)C1=CC2=CC=CC=C2OC1=O)OC
InChiKey:
SNICUMZYPOCXCO-UHFFFAOYSA-N
InChi :
InChI=1S/C22H21NO4/c1-22(2)12-14-10-18(25-3)19(26-4)11-15(14)20(23-22)16-9-13-7-5-6-8-17(13)27-21(16)24/h5-11H,12H2,1-4H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 selectively activates TRPC6 over other TRP channels and also activates TRPA1. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50=2.37 μM).|Product information|CAS Number: 667427-75-0|Molecular Weight: 363.41|Formula: C22H21NO4|Chemical Name: 3-(6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-2H-chromen-2-one|Smiles: CC1(C)CC2C=C(OC)C(=CC=2C(=N1)C1=CC2=CC=CC=C2OC1=O)OC|InChiKey: SNICUMZYPOCXCO-UHFFFAOYSA-N|InChi: InChI=1S/C22H21NO4/c1-22(2)12-14-10-18(25-3)19(26-4)11-15(14)20(23-22)16-9-13-7-5-6-8-17(13)27-21(16)24/h5-11H,12H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{β-Carotene} MedChemExpress|{β-Carotene} Immunology/Inflammation|{β-Carotene} Technical Information|{β-Carotene} Purity|{β-Carotene} custom synthesis|{β-Carotene} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{(-)-Ketoconazole} medchemexpress|{(-)-Ketoconazole} Anti-infection|{(-)-Ketoconazole} Purity & Documentation|{(-)-Ketoconazole} Formula|{(-)-Ketoconazole} manufacturer|{(-)-Ketoconazole} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24268253 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
