Product Name :
β, β-Dimethylacrylshikonin
Description:
β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative isolated from Arnebia nobilis, promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.β,β-Dimethylacrylshikonin has anti-tumor activity.
CAS:
24502-79-2
Molecular Weight:
370.40
Formula:
C21H22O6
Chemical Name:
(1R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl 3-methylbut-2-enoate
Smiles :
CC(C)=CC(=O)O[C@H](CC=C(C)C)C1=CC(=O)C2C(C1=O)=C(O)C=CC=2O
InChiKey:
BATBOVZTQBLKIL-QGZVFWFLSA-N
InChi :
InChI=1S/C21H22O6/c1-11(2)5-8-17(27-18(25)9-12(3)4)13-10-16(24)19-14(22)6-7-15(23)20(19)21(13)26/h5-7,9-10,17,22-23H,8H2,1-4H3/t17-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative isolated from Arnebia nobilis, promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.β,β-Dimethylacrylshikonin has anti-tumor activity.|Product information|CAS Number: 24502-79-2|Molecular Weight: 370.40|Formula: C21H22O6|Synonym:|Isoarnebin I|Chemical Name: (1R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl 3-methylbut-2-enoate|Smiles: CC(C)=CC(=O)O[C@H](CC=C(C)C)C1=CC(=O)C2C(C1=O)=C(O)C=CC=2O|InChiKey: BATBOVZTQBLKIL-QGZVFWFLSA-N|InChi: InChI=1S/C21H22O6/c1-11(2)5-8-17(27-18(25)9-12(3)4)13-10-16(24)19-14(22)6-7-15(23)20(19)21(13)26/h5-7,9-10,17,22-23H,8H2,1-4H3/t17-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 25 mg/mL (67.{{Fenbendazole} web|{Fenbendazole} Cell Cycle/DNA Damage|{Fenbendazole} Biological Activity|{Fenbendazole} In stock|{Fenbendazole} manufacturer|{Fenbendazole} Cancer} 49 mM; Need ultrasonic).{{Fezolinetant} MedChemExpress|{Fezolinetant} Neurokinin Receptor|{Fezolinetant} Technical Information|{Fezolinetant} In stock|{Fezolinetant} supplier|{Fezolinetant} Epigenetics} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23776646 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Zeng Z, et al. Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Int J Mol Med. 2015 Sep;36(3):685-97.Sidhu GS, et al. Arnebin-1 accelerates normal and hydrocortisone-induced impaired wound healing. J Invest Dermatol. 1999 Nov;113(5):773-81.Products are for research use only. Not for human use.|
