Product Name :
(R)-HH2853
Description:
(R)-HH2853 is a mutant EZH2 inhibitor with an IC50 of <100 nM for EZH2-Y641F. (R)-HH2853 can be used for cancer and autoimmune diseases (WO2018045971A1; compound 201).
CAS:
2202678-06-4
Molecular Weight:
611.66
Formula:
C31H36F3N7O3
Chemical Name:
Smiles :
CC1=CC=C(N=N1)C1C=CN2C([C@@H](C)N3CCN(CC(F)(F)F)CC3)=C(C)C(=CC2=1)C(=O)NCC1=C(C=C(C)NC1=O)OC
InChiKey:
BIABSPVTTUDBEO-OAQYLSRUSA-N
InChi :
InChI=1S/C31H36F3N7O3/c1-18-6-7-25(38-37-18)22-8-9-41-26(22)15-23(29(42)35-16-24-27(44-5)14-19(2)36-30(24)43)20(3)28(41)21(4)40-12-10-39(11-13-40)17-31(32,33)34/h6-9,14-15,21H,10-13,16-17H2,1-5H3,(H,35,42)(H,36,43)/t21-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(R)-HH2853 is a mutant EZH2 inhibitor with an IC50 of Product information|CAS Number: 2202678-06-4|Molecular Weight: 611.{{Asfotase alfa} site|{Asfotase alfa} Protocol|{Asfotase alfa} In Vitro|{Asfotase alfa} manufacturer|{Asfotase alfa} Epigenetics} 66|Formula: C31H36F3N7O3|Smiles: CC1=CC=C(N=N1)C1C=CN2C([C@@H](C)N3CCN(CC(F)(F)F)CC3)=C(C)C(=CC2=1)C(=O)NCC1=C(C=C(C)NC1=O)OC|InChiKey: BIABSPVTTUDBEO-OAQYLSRUSA-N|InChi: InChI=1S/C31H36F3N7O3/c1-18-6-7-25(38-37-18)22-8-9-41-26(22)15-23(29(42)35-16-24-27(44-5)14-19(2)36-30(24)43)20(3)28(41)21(4)40-12-10-39(11-13-40)17-31(32,33)34/h6-9,14-15,21H,10-13,16-17H2,1-5H3,(H,35,42)(H,36,43)/t21-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ropivacaine} MedChemExpress|{Ropivacaine} Membrane Transporter/Ion Channel|{Ropivacaine} Technical Information|{Ropivacaine} Description|{Ropivacaine} supplier|{Ropivacaine} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:23991096 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:| Xuxing Chen, et al. Pyrido five-element aromatic ring compound, preparation method therefor and use thereof. WO2018045971A1. Products are for research use only. Not for human use.|
