Product Name :
MS-PEG4-THP
Description:
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
145927-73-7
Molecular Weight:
356.43
Formula:
C14H28O8S
Chemical Name:
2-(2-{2-[2-(oxan-2-yloxy)ethoxy]ethoxy}ethoxy)ethyl methanesulfonate
Smiles :
CS(=O)(=O)OCCOCCOCCOCCOC1CCCCO1
InChiKey:
IHVHEXYPQZJGKH-UHFFFAOYSA-N
InChi :
InChI=1S/C14H28O8S/c1-23(15,16)22-13-11-19-9-7-17-6-8-18-10-12-21-14-4-2-3-5-20-14/h14H,2-13H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 145927-73-7|Molecular Weight: 356.43|Formula: C14H28O8S|Chemical Name: 2-(2-{2-[2-(oxan-2-yloxy)ethoxy]ethoxy}ethoxy)ethyl methanesulfonate|Smiles: CS(=O)(=O)OCCOCCOCCOCCOC1CCCCO1|InChiKey: IHVHEXYPQZJGKH-UHFFFAOYSA-N|InChi: InChI=1S/C14H28O8S/c1-23(15,16)22-13-11-19-9-7-17-6-8-18-10-12-21-14-4-2-3-5-20-14/h14H,2-13H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Rovalpituzumab} site|{Rovalpituzumab} Notch|{Rovalpituzumab} Biological Activity|{Rovalpituzumab} In Vitro|{Rovalpituzumab} custom synthesis|{Rovalpituzumab} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Xevinapant} web|{Xevinapant} Apoptosis|{Xevinapant} Biological Activity|{Xevinapant} References|{Xevinapant} manufacturer|{Xevinapant} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24507727 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
