Product Name :
N-(Azido-PEG4)-N-bis(PEG4-NHS ester)
Description:
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2353409-90-0
Molecular Weight:
981.01
Formula:
C41H68N6O21
Chemical Name:
2,5-dioxopyrrolidin-1-yl 1-(1-azido-N-{15-[(2,5-dioxopyrrolidin-1-yl)oxy]-15-oxo-3,6,9,12-tetraoxapentadecan-1-yl}-3,6,9,12-tetraoxapentadecan-15-amido)-3,6,9,12-tetraoxapentadecan-15-oate
Smiles :
[N-]=[N+]=NCCOCCOCCOCCOCCC(=O)N(CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey:
OYVKKJHNNQYSIS-UHFFFAOYSA-N
InChi :
InChI=1S/C41H68N6O21/c42-44-43-8-14-58-20-26-64-32-29-61-23-17-55-11-5-35(48)45(9-15-59-21-27-65-33-30-62-24-18-56-12-6-40(53)67-46-36(49)1-2-37(46)50)10-16-60-22-28-66-34-31-63-25-19-57-13-7-41(54)68-47-38(51)3-4-39(47)52/h1-34H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Podofilox} medchemexpress|{Podofilox} Cytoskeleton|{Podofilox} Protocol|{Podofilox} In Vitro|{Podofilox} supplier|{Podofilox} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Fenoverine} site|{Fenoverine} Neuronal Signaling|{Fenoverine} Protocol|{Fenoverine} References|{Fenoverine} custom synthesis|{Fenoverine} Autophagy}
Additional information:
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.PMID:23671446 |Product information|CAS Number: 2353409-90-0|Molecular Weight: 981.01|Formula: C41H68N6O21|Chemical Name: 2,5-dioxopyrrolidin-1-yl 1-(1-azido-N-{15-[(2,5-dioxopyrrolidin-1-yl)oxy]-15-oxo-3,6,9,12-tetraoxapentadecan-1-yl}-3,6,9,12-tetraoxapentadecan-15-amido)-3,6,9,12-tetraoxapentadecan-15-oate|Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCC(=O)N(CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O|InChiKey: OYVKKJHNNQYSIS-UHFFFAOYSA-N|InChi: InChI=1S/C41H68N6O21/c42-44-43-8-14-58-20-26-64-32-29-61-23-17-55-11-5-35(48)45(9-15-59-21-27-65-33-30-62-24-18-56-12-6-40(53)67-46-36(49)1-2-37(46)50)10-16-60-22-28-66-34-31-63-25-19-57-13-7-41(54)68-47-38(51)3-4-39(47)52/h1-34H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
