The CPCP intervention group have been related to gut microbiota membership (Figures S2B and compovention group were associated with gut microbiota membership (Figures S2B and S3B) or S3B) or composition (Figures S2D and S3D). Similarly, lipocalin-2 nor calprotectin concentrations sition (Figures S2D and S3D). Similarly, neither neither lipocalin-2 nor calprotectin concentrations inside the participants who consumed only tomato tomato juice have been associated gut in the stools of stools of participants who consumed onlyjuice had been connected with thewith the gut microbiota membership (Figures S2A and S3A) or composition and S3C) working with microbiota membership (Figures S2A and S3A) or composition (Figure S2C(Figure S2C and S3C) utilizing Bray urtis dissimilarities, respectively. These with higher lipocalin-2 levels Sorensen andSorensen and Bray urtis dissimilarities, respectively. These with larger lipocalin-2 levels exhibited higher of Blautia, Anaerostipes, Alphaproteobacteria_unclassified, exhibited higher relative abundance relative abundance of Blautia, Anaerostipes, Alphaproteobacteria_unclassified, andcalprotectin levels improved so didlevels improved so did the and Anaerosporobacter.IL-1 beta Protein manufacturer As Anaerosporobacter.Carboxylesterase 1 Protein manufacturer As calprotectin the relative abundance of relative abundance of Eubacterium (Table three). Eubacterium and Pseudoflavonifractorand Pseudoflavonifractor (Table three).Table 3. Correlation of gut microbiota taxa at genus level and lipocalin-2 or calprotectin levels. Taxa Blautia Anaerostipes Alphaproteobacteria_unclassified Anaerosporobacter Eubacterium Pseudoflavonifractor Coefficient 0.15 0.20 0.24 0.05 0.15 0.12 p-Value 0.003 0.003 0.001 0.009 0.001 0.003 q-Value 0.ten 0.10 0.ten 0.24 0.10 0.Lipocalin-CalprotectinLife 2022, 12,ten of4. Discussion Our study aimed to ascertain the influence of CP on human gut microbiota and intestinal inflammation in vivo. We found that CP consumption did not influence the gut microbial alpha and beta diversity with or without BMI stratification. Participants who consumed CP had a significantly lower relative abundance of Oscillibacter and Phascolarctobacterium, but a greater abundance of Bifidobacterium and Gp6. Stool concentrations of lipocalin-2 and calprotectin were comparable before and right after CP consumption.PMID:23600560 Nevertheless, lipocalin-2 and calprotectin levels had been positively correlated within the CP consumption group. Neither lipocalin-2 nor calprotectin levels have been related to gut microbial composition. Thus, CP consumption at 1.eight g per day had minimal effect on either the gut microbiota composition or intestinal inflammation within this pilot study. Emerging proof suggests that polyphenol-rich foods, including spices, have prospective as prebiotics that will promote the growth of probiotics, including Bifidobacterium spp. and Lactobacillus spp., and inhibit the growth of pathogenic bacteria for example Clostridium spp. [12,36]. Culinary spices like black pepper, cayenne pepper, and cinnamon enhanced the development of Bifidobacterium spp. And Lactobacillus spp. In vitro [12]. An increased abundance of Bifidobacterium and Lactobacillus, as well as a decreased abundance of Clostridium have been discovered in participants who consumed a spice mixture containing cinnamon, oregano, ginger, black pepper, and cayenne pepper [36]. In addition to spices, red wine, wild blueberries and tart cherries also have already been demonstrated to boost Bifidobacterial populations [379]. Many research demonstrate that distinct species of Bifidobacteria exhibit anti-infection properties, al.
