Meliorate oxidative strain and inflammation in sufferers with end-stage renal disease. J Natl Med Assoc 101: 336344. 11. Mann JF, 1317923 Lonn EM, Yi Q, Gerstein HC, Hoogwerf BJ, Pogue J, et al. Effects of vitamin E on cardiovascular KDM5A-IN-1 web outcomes in individuals with mild-tomoderate renal insufficiency: final results of your HOPE study. Kidney Int 65: 1375 1380. 12. Schnackenberg CG, Wilcox CS Two-week administration of tempol attenuates each hypertension and renal excretion of 8-Iso prostaglandin f2alpha. Hypertension 33: 424428. 13. Nishiyama A, Yoshizumi M, Hitomi H, Kagami S, Kondo S, et al. The SOD mimetic tempol ameliorates glomerular injury and reduces mitogenactivated protein kinase activity in Dahl salt-sensitive rats. J Am Soc Nephrol 15: 306315. 14. Beswick RA, Zhang H, Marable D, Catravas JD, Hill WD, et al. Longterm antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response. Hypertension 37: 781786. 15. Vaziri ND, Ding Y, Ni Z Compensatory up-regulation of nitric-oxide synthase isoforms in lead-induced hypertension; reversal by a superoxide dismutase-mimetic drug. J Pharmacol Exp Ther 298: 679685. 16. Rancourt ME, Rodrigue ME, Agharazii M, Lariviere R, Lebel M Role of oxidative anxiety in erythropoietin-induced hypertension in uremic rats. Am J Hypertens 23: 314320. 17. Koeners MP, Braam B, Joles JA Perinatal inhibition of NF-kappaB has long-term antihypertensive effects in spontaneously hypertensive 1315463 rats. J Hypertens 29: 11601166. 18. Schnackenberg CG, Welch WJ, Wilcox CS Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: function of nitric oxide. Hypertension 32: 5964. 19. Guron GS, Grimberg ES, Basu S, Herlitz H Acute effects with the superoxide dismutase mimetic tempol on split kidney function in two-kidney one-clip hypertensive rats. J Hypertens 24: 387394. 20. Hasdan G, Benchetrit S, Rashid G, Green J, Bernheim J, et al. Endothelial dysfunction and hypertension in 5/6 nephrectomized rats are mediated by vascular superoxide. Kidney Int 61: 586590. 21. Quiroz Y, Ferrebuz A, Vaziri ND, Rodriguez-Iturbe B Impact of chronic antioxidant therapy with superoxide dismutase-mimetic drug, tempol, on progression of renal disease in rats with renal mass reduction. Nephron Exp Nephrol 112: e31e42. 22. Hughes JM, Bund SJ Influence of experimental reduction of media/ lumen ratio on arterial myogenic properties of spontaneously hypertensive and Wistar-Kyoto rats. Clin Sci 106: 163171. 23. Sousa T, Pinho D, Morato M, Marques-Lopes J, Fernandes E, et al. Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors. Eur J Pharmacol 588: 267276. 24. Sousa T, Oliveira S, Afonso J, Morato M, Patinha D, et al. Role of HO in hypertension, renin-angiotensin system activation and renal medullary disfunction caused by angiotensin II. Br J Pharmacol 166: 23862401. 25. Bongartz LG, Braam B, Verhaar MC, Cramer MJ, Goldschmeding R, et al. Transient nitric oxide reduction induces permanent cardiac systolic dysfunction and worsens kidney harm in rats with chronic kidney illness. Am J Physiol Regul Integr Comp Physiol 298: R815R823. 26. Quiroz Y, Pons H, Gordon KL, Rincon J, Chavez M, et al. Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition. Am J Physiol Renal Physiol 281: BIBS39 F38F47. 27. Blezer EL, Schurink M, Nicolay K, Bar PR, Jansen GH, et al. Proteinuria precedes cere.Meliorate oxidative anxiety and inflammation in sufferers with end-stage renal illness. J Natl Med Assoc 101: 336344. 11. Mann JF, 1317923 Lonn EM, Yi Q, Gerstein HC, Hoogwerf BJ, Pogue J, et al. Effects of vitamin E on cardiovascular outcomes in people today with mild-tomoderate renal insufficiency: benefits from the HOPE study. Kidney Int 65: 1375 1380. 12. Schnackenberg CG, Wilcox CS Two-week administration of tempol attenuates each hypertension and renal excretion of 8-Iso prostaglandin f2alpha. Hypertension 33: 424428. 13. Nishiyama A, Yoshizumi M, Hitomi H, Kagami S, Kondo S, et al. The SOD mimetic tempol ameliorates glomerular injury and reduces mitogenactivated protein kinase activity in Dahl salt-sensitive rats. J Am Soc Nephrol 15: 306315. 14. Beswick RA, Zhang H, Marable D, Catravas JD, Hill WD, et al. Longterm antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response. Hypertension 37: 781786. 15. Vaziri ND, Ding Y, Ni Z Compensatory up-regulation of nitric-oxide synthase isoforms in lead-induced hypertension; reversal by a superoxide dismutase-mimetic drug. J Pharmacol Exp Ther 298: 679685. 16. Rancourt ME, Rodrigue ME, Agharazii M, Lariviere R, Lebel M Function of oxidative strain in erythropoietin-induced hypertension in uremic rats. Am J Hypertens 23: 314320. 17. Koeners MP, Braam B, Joles JA Perinatal inhibition of NF-kappaB has long-term antihypertensive effects in spontaneously hypertensive 1315463 rats. J Hypertens 29: 11601166. 18. Schnackenberg CG, Welch WJ, Wilcox CS Normalization of blood pressure and renal vascular resistance in SHR using a membrane-permeable superoxide dismutase mimetic: function of nitric oxide. Hypertension 32: 5964. 19. Guron GS, Grimberg ES, Basu S, Herlitz H Acute effects with the superoxide dismutase mimetic tempol on split kidney function in two-kidney one-clip hypertensive rats. J Hypertens 24: 387394. 20. Hasdan G, Benchetrit S, Rashid G, Green J, Bernheim J, et al. Endothelial dysfunction and hypertension in 5/6 nephrectomized rats are mediated by vascular superoxide. Kidney Int 61: 586590. 21. Quiroz Y, Ferrebuz A, Vaziri ND, Rodriguez-Iturbe B Effect of chronic antioxidant therapy with superoxide dismutase-mimetic drug, tempol, on progression of renal illness in rats with renal mass reduction. Nephron Exp Nephrol 112: e31e42. 22. Hughes JM, Bund SJ Influence of experimental reduction of media/ lumen ratio on arterial myogenic properties of spontaneously hypertensive and Wistar-Kyoto rats. Clin Sci 106: 163171. 23. Sousa T, Pinho D, Morato M, Marques-Lopes J, Fernandes E, et al. Part of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors. Eur J Pharmacol 588: 267276. 24. Sousa T, Oliveira S, Afonso J, Morato M, Patinha D, et al. Part of HO in hypertension, renin-angiotensin program activation and renal medullary disfunction caused by angiotensin II. Br J Pharmacol 166: 23862401. 25. Bongartz LG, Braam B, Verhaar MC, Cramer MJ, Goldschmeding R, et al. Transient nitric oxide reduction induces permanent cardiac systolic dysfunction and worsens kidney damage in rats with chronic kidney disease. Am J Physiol Regul Integr Comp Physiol 298: R815R823. 26. Quiroz Y, Pons H, Gordon KL, Rincon J, Chavez M, et al. Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition. Am J Physiol Renal Physiol 281: F38F47. 27. Blezer EL, Schurink M, Nicolay K, Bar PR, Jansen GH, et al. Proteinuria precedes cere.
